Hello, welcome to LABINC!!
The Bioinorganic and Crystallography Laboratory (LABINC) was created in January 1988 by Professor Ademir Neves, shortly after his return from a postdoctoral fellowship in 1987 with Professor Karl Wieghardt at the Institut für Anorganische Chemie I of Ruhr Universität Bochum.
LABINC started its work with 3 doctoral students, 1 master’s student, and 2 undergraduate students. The research focused on the synthesis and characterization of new structural models for mononuclear metalloenzymes of the vanadium and iron-transferrin types and dinuclear iron for the active site of purple acid phosphatases. The group had financial support from CNPq and FINEP. In 1994, FINEP supported the installation of the first X-ray diffractometer for monocrystals in the southern region of the country.
In the late 1990s, the group expanded its research lines, initiating work involving structural and functional models for the metalloenzymes Purple Acid Phosphatases and Catechol Oxidases. At that time, scientific collaboration began with Professor Hernán Terenzi, involving the use of biomimetic models in the cleavage of nucleic acids and proteins.
Starting in 2010, with the joining of Professor Rosely Aparecida Peralta, the group expanded its research lines to include topics such as Carbon Monoxide Photoliberation and Ethylene Photodegradation.
LABINC’s mission is to develop high-quality multidisciplinary research at the forefront of knowledge.
Some of the group’s research lines involve the following topics:
- Metallopharmaceuticals for the treatment of cardiovascular, gastric, infectious, and cancerous diseases
- Bioinspired Metallohydrolases and Catecholases
- Investigation of reactivity and mechanistic aspects of coordination compounds and their biological targets
- Homogeneous and heterogeneous catalysis
- Photochemistry of organometallic compounds for use in photodynamic therapy (PhotoCORMs)
- Synthesis of inorganic and hybrid nanostructured materials, Sol-gel method, and heterogeneous photocatalysis
